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Novel treatment (new drug/intervention; established drug/procedure in new situation)
Resolution of severe hepato-pulmonary syndrome following transjugular portosystemic shunt procedure
  1. Michael C Wallace1,
  2. Alan L James2,3,
  3. Martin Marshall4,
  4. Nickolas Kontorinis1
  1. 1Department of Gastroenterology and Hepatology, Royal Perth Hospital, Perth, Western Australia, Australia
  2. 2School of Medicine and Pharmacology, University of Western Australia, Perth, Western Australia, Australia
  3. 3West Australian Sleep Disorders Research Institute, Sir Charles Gairdner Hospital, Perth, Western Australia, Australia
  4. 4Department of Diagnostic and Interventional Radiology, Royal Perth Hospital, Perth, Western Australia, Australia
  1. Correspondence to Dr Michael C Wallace, michael.wallace2{at}health.wa.gov.au

Summary

The hepato-pulmonary syndrome (HPS) is a relatively common complication of hepatic disease that leads to hypoxaemia and dyspnoea secondary to pulmonary shunting. A number of pharmacological therapies have been trialled, yet liver transplantation remains the only definitive treatment. The use of a transjugular intrahepatic portosystemic shunt (TIPS) to reduce portal hypertension and improve oxygenation remains controversial in HPS due to the lack of large clinical series or randomised controlled trials. We present a case of HPS successfully treated with TIPS and review the relevant literature.

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Footnotes

  • Competing interests None.

  • Patient consent Obtained.