BMJ Case Reports 2012; doi:10.1136/bcr.02.2012.5743
  • Unusual association of diseases/symptoms

Tumefactive demyelination associated with systemic lupus erythematosus

  1. Kamal Arya2
  1. 1Department of Neurology, Chhatrapati Shahuji Maharaj Medical University, Lucknow, UP, India
  2. 2PDU Institute for the Physically Handicapped, University of Delhi, Dehli, India
  1. Correspondence to Professor Rajesh Verma, drrajeshverma32{at}


Systemic lupus erythematosus (SLE) is a chronic inflammatory multi-system disease characterised by varied clinical manifestation and immunological abnormalities. The clinical presentation of the disorder has wide spectra, from an asymptomatic presentation to a severe life-threatening disease affecting several organs. The sole manifestation of lupus erythematosus could be neurological syndrome, where diagnosis of SLE is difficult to establish. The authors intended to report a young female, who initially developed left-sided hemiparesis due to tumefactive demyelination, later on diagnosed as case of SLE. The association of tumefactive demyelination and SLE has not been previously reported in the literature.


  • Competing interests None.

  • Patient consent Obtained.

Register for free content

The full text of all Editor's Choice articles and summaries of every article are free without registration

The full text of Images in ... articles are free to registered users

Only fellows can access the full text of case reports (apart from Editor's Choice) - become a fellow today, or encourage your institution to, so that together we can grow and develop this resource

Don't forget to sign up for content alerts so you keep up to date with all the case reports as they are published, and let us know what you think by commenting on the Editor's blog

Navigate This Article