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BMJ Case Reports 2012; doi:10.1136/bcr.01.2012.5685
  • Unusual presentation of more common disease/injury

T cell acute lymphoblastic leukaemia presenting with sudden onset right oculomotor nerve palsy with normal neuroradiography and cerebrospinal fluid studies

  1. Qun Dai2
  1. 1Department Of Medicine, Staten Island University Hospital, Staten Island, New York, USA
  2. 2Division Of Hematology/Oncology, Department of Medicine, Sanford R Nalitt Institute for Cancer and Blood Related Diseases, Staten Island University Hospital, Staten Island, New York, USA
  1. Correspondence to Dr Srujitha Murukutla, srujitha.murukutla{at}gmail.com

Summary

Leptomeningeal disease presenting with neurological dysfunction is not uncommon in leukaemia. However, it is often accompanied by abnormalities in cerebrospinal fluid (CSF) studies and/or neuroradiography. Here, the authors describe a case of a young patient presenting with sudden onset right oculomotor nerve palsy with normal neuroradiography and CSF studies, who was subsequently diagnosed to have T cell acute lymphoblastic leukaemia (T-ALL). This case highlights that neurological manifestations can be the initial presenting feature of T-ALL and can occur suddenly despite normal neuroradiography and initial CSF studies.

Footnotes

  • Competing interests None.

  • Patient consent Obtained.

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