BMJ Case Reports 2012; doi:10.1136/bcr.01.2012.5641
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Wheat-dependent exercise-induced anaphylaxis associated with a facial soap

  1. Eiji Kusumi1,4
  1. 1Department of Internal Medicine, Navitas Clinic, Tachikawa, Japan
  2. 2Department of Hematology and Rheumatology, Teikyo Universiy Chiba Medical Center, Ichihara, Japan
  3. 3Cancer Institute, Japanese Foundation for Cancer Research, Tokyo, Japan
  4. 4Division of Social Communication System for Advanced Clinical Research, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan
  1. Correspondence to Dr Tetsuya Tanimoto, tetanimot{at}


A 27-year-old woman presented to our clinic with sudden-onset of nasal discharge and bilateral periorbital oedema (figures 1 and 2). Although she had been well until the morning, she noticed the extensive, rapidly progressing symptom during exercise at gymnasium after lunch containing fried-wheat. She had no history of food allergies. We performed a radioallergosorbent test, and it was positive for wheat. We made a diagnosis of so-called, wheat-dependent exercise-induced anaphylaxis …

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