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BMJ Case Reports 2012; doi:10.1136/bcr-2012-007046
  • Reminder of important clinical lesson

The clinical management in familial adenomatous polyposis deserves continuous monitoring for thyroid carcinoma

  1. Luca Mazzucchelli1
  1. 1Institute of Pathology, Locarno, Switzerland
  2. 2Department of Medical Oncology, Oncology Institute of Southern Switzerland, Bellinzona, Switzerland
  1. Correspondence to Dr Stefano Crippa, stefano.crippa{at}ti.ch

Summary

Papillary thyroid carcinoma is an extraintestinal manifestation of patients with familial adenomatous polyposis, mainly occurring in young women. Recent publications highlight that familial adenomatous polyposis-associated papillary thyroid carcinoma represents a distinct type of follicular cell neoplasm histologically characterised by cribriform-morular aspects, the incidence of which has probably been underestimated so far. We report a case history of familial adenomatous polyposis-associated papillary thyroid carcinoma occurring in a 55-year-old man with Gardner syndrome, underscoring the importance of careful ultrasound screening examination of the thyroid gland in this condition.

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