BMJ Case Reports 2012; doi:10.1136/bcr-2012-006731
  • Rare disease

Antiphospholipid syndrome presenting with acute digital ischaemia, avascular necrosis of the femoral head and superior mesenteric artery thrombus

  1. Nicholas Fluck2
  1. 1Department of Vascular Surgery, Aberdeen Royal Infirmary, Aberdeen, UK
  2. 2Department of Renal Medicine, Aberdeen Royal Infirmary, Aberdeen, UK
  1. Correspondence to Dr Christopher Robert Crome, c.crome{at}


This case illustrates a rare and unique case of a 73-year-old woman who presents with a rapidly developing digital ischaemia, superior mesenteric artery thrombus with positive-lupus anticoagulant. She then developed avascular necrosis of the femoral head. Discussion of the process of diagnosis and management of antiphospholipid syndrome and catastrophic antiphospholipid syndrome are reported.

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