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  • Development of Graves’ disease after long-standing hypothyroidism on treatment, with acute toxicity to thionamides and lithium

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Unusual presentation of more common disease/injury
Development of Graves’ disease after long-standing hypothyroidism on treatment, with acute toxicity to thionamides and lithium
  1. Yashdeep Gupta1,
  2. Sandeep Singh2,
  3. Ariachery C Ammini1
  1. 1Department of Endocrinology and Metabolism, All India Institute of Medical Sciences, New Delhi, India
  2. 2Department of Cardiology, All India Institute of Medical Sciences, New Delhi, India
  1. Correspondence to Professor Ariachery C Ammini, aca433{at}yahoo.com

Thyroid hyperfunction in a patient with long-standing hypothyroidism is uncommon. Here, we describe and discuss the unusual scenario of development of severe skin rash to carbimazole, with subsequent acute toxicity to lithium in clinically indicated doses, in a patient who manifested hyperthyroidism after being on treatment for hypothyroidism for 7 years.

https://doi.org/10.1136/bcr-2012-006433

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    Footnotes

    • Competing interests None.

    • Patient consent Obtained.