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Rare disease
Mediastinal germ cell tumour with massive pulmonary involvement
  1. Kenji Kawamukai1,
  2. Salomone Di Saverio2,
  3. Filippo Antonacci1,
  4. Nicola Lacava1,
  5. Maurizio Boaron1
  1. 1Department of Thoracic Surgery, Maggiore and Bellaria Hospitals, Bologna, Italy
  2. 2Department of Surgery and Emergency, Emergency and Trauma Surgery Unit (Head Professor F. Baldoni), Bologna Local Health District, Maggiore Hospital Trauma Center, University of Bologna, Bologna, Italy
  1. Correspondence to Dr Salomone Di Saverio, salo75{at}inwind.it

Summary

Multimodality treatment, with chemotherapy and surgery, is potentially curative in case of non-seminomatous germ cell tumours. The authors present the case of a primitive mediastinal GTC with bilateral lung metastases. The patient was treated with five cycles of chemotherapy. Restaging showed reduction of the extent and of 18 FDG intake and β-HCG serum levels. The patient underwent two-step surgical excision of the tumours: mediastinal lesion and 35 lung metastases were resected by a right thoracotomy and 39 metastases were removed by a left thoracotomy. Histology showed absence of viable tumour in all the specimens. Twelve months after surgery the patient is free of disease.

https://doi.org/10.1136/bcr.12.2010.3671

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    Footnotes

    • Competing interests None.

    • Patient consent Obtained.