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Rare disease
Bronchogenic adenocarcinoma presenting as a synchronous solitary lytic skull lesion with ischaemic stroke – case report and literature review
  1. David O’Connell1,
  2. Chandrasekaran Kaliaperumal1,
  3. Gerald Wyse2,
  4. Julie McCarthy3,
  5. Aisling Ryan4
  1. 1Department of Neurosurgery, Cork University Hospital, Cork, Ireland
  2. 2Department of Neuroradiology, Cork Univsersity Hospital, Cork, Ireland
  3. 3Department of Pathology, Cork University Hospital, Cork, Ireland
  4. 4Department of Neurology, Cork University Hospital, Cork, Ireland
  1. Correspondence to Mr Chandrasekaran Kaliaperumal, ckaliaperumal{at}gmail.com

Summary

The authors describe a rare case of metastatic bronchogenic adenocarcinoma in a 55-year-old man presenting with concomittant solitary lytic skull lesion and ischaemic stroke. Metastatic bronchogenic carcinoma is known to present as lytic skull lesions. Primary brain tumours are also known to cause ischaemic brain injury. An underlying stroke risk may be exagerated by cranial tumour surgery. Patients with brain tumours are well known to be predisposed to an increased risk of developing thromboembolic disease. It is unusual to see metastatic bronchogenic adenocarcinoma presenting as ischaemic stroke with a background of concomittant cerebral metastasis. The aetio-pathogenesis of this rare occurrence is discussed with a review of literature.

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Footnotes

  • Competing interests None.

  • Patient consent Obtained.