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Rare disease
Chloramphenicol – not so innocuous: a case of optic neuritis
  1. Adrian T Fung1,3,
  2. Bernard Hudson2,
  3. Frank A Billson2,3
  1. 1Sydney Eye Hospital, Sydney, New South Wales, Australia
  2. 2Department of Microbiology and Infectious Diseases, PaLMS, Royal North Shore Hospital, Sydney, New South Wales, Australia
  3. 3Discipline of Clinical Ophthalmology and Eye Health, University of Sydney Medical School, Sydney, New South Wales, Australia
  1. Correspondence to Adrian T Fung, adrianfungi{at}yahoo.com.au

Summary

The authors present a case of optic neuritis in an adult patient who had been self-prescribing extraordinarily large dosages of chloramphenicol for chronic prostatitis over several years. The visual symptoms resolved upon cessation of the drug and prescription of B group vitamins. Chloramphenicol optic neuritis has not been described in the literature for over 20 years and previously predominantly in children with cystic fibrosis.

https://doi.org/10.1136/bcr.10.2010.3434

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    Footnotes

    • Competing interests None.

    • Patient consent Obtained.