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BMJ Case Reports 2011; doi:10.1136/bcr.08.2011.4641
  • Unusual presentation of more common disease/injury

Permanent haemichorea associated with transient hyperglycemia

  1. Terra Arnason3
  1. 1Department of Medicine, University of Alberta, Edmonton, Canada
  2. 2Department of Neurology, University of Saskatchewan, Saskatoon, Canada
  3. 3Department of Medicine, University of Saskatchewan, Saskatoon, Canada
  1. Correspondence to Dr Terra Arnason, terra.arnason{at}usask.ca

Summary

Hyperglycemia is associated with several common neurological syndromes. Chorea, however, is a rare association that has only been documented in the literature recently. The triad of chorea, non-ketotic hyperglycemia and a high signal basal ganglia lesion on the T1 weighted brain MRI (C-H-BG) is considered to be a unique syndrome. C-H-BG refers to the onset of chorea during or shortly after (days to weeks) an episode of non-ketotic hyperglycemia. There is usually a high signal lesion in the basal ganglia on T1 weighted brain MRI that corresponds to the location of the chorea. Most case reports of C-H-BG have been described in Asians. C-H-BG is considered to be a benign condition in which the clinical and MRI signs resolve quickly upon correction of blood glucose levels. Here, the authors describe a case of C-H-BG in a middle aged Caucasian in whom the chorea did not resolve with improved glycemic control.

Footnotes

  • Competing interests None.

  • Patient consent Obtained.

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