Article Text

Download PDFPDF
Findings that shed new light on the possible pathogenesis of a disease or an adverse effect
Fusobacterium necrophorum – beyond Lemierres syndrome
  1. Lokesh Shahani1,
  2. Nancy Khardori2
  1. 1Department of Internal Medicine, Southern Illinois University School of Medicine, Springfield, Illinois, United States
  2. 2Divison of Infectious Disease, Department of Internal Medicine, SIU School of Medicine, Springfield, Illinois, United States
  1. Correspondence to Dr Lokesh Shahani, lokesh83{at}hotmail.com

Summary

Fusobacterium necrophorum is a non-sporulating anaerobic gram negative bacillus and has traditionally been associated with Lemierre’s syndrome. The authors report a 34-year-old male who presented to the emergency department with a week’s history of dull epigastirc pain. Significant medical history included chronic pancreatitis secondary to alcohol use. The patient had radiological evidence of acute on chronic pancreatitis with thrombosis of the portal vein and multiple intrahepatic abscesses. CT-guided drainage of left upper quadrant revealed fluid collection in the pancreatic bed. The fluid culture grew F necrophorum and the patient was treated with tigecycline for 4 weeks. The patient improved symptomatically and his follow-up computerised axial tomography scan 2 months later showed resolving liver abscess, cavernous transformation of the portal vein and stable findings of chronic pancreatitis. This could represent an infection of the peripancreatic tissue with F necrophorum further leading to pylephlebitis.

Statistics from Altmetric.com

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.

Footnotes

  • Competing interests None.

  • Patient consent Obtained.