BMJ Case Reports 2011; doi:10.1136/bcr.06.2011.4384
  • Rare disease

The first documented case of Candida dubliniensis leptomeningeal disease in an immunocompetent host

  1. Genevieve Gabb1
  1. 1Department of Medicine, Royal Adelaide Hospital, Adelaide, South Australia, Australia
  2. 2Department of Geriatric Medicine, Royal Adelaide Hospital, Adelaide, South Australia, Australia
  1. Correspondence to Dr Nicholas Howard Andrew, nick.h.andrew{at}


In June 2008, a 25-year-old man presented to the Royal Adelaide Hospital, Australia, with Candida dubliniensis leptomeningeal disease. On examination the patient had focal neurological deficits, both sensory and motor. He tested negative for HIV and had normal T cell subsets. The patient was treated with 6 weeks of intravenous liposomal amphotericin B and oral flucytosine, and had a full recovery.


  • Competing interests None.

  • Patient consent Obtained.

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