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BMJ Case Reports 2011; doi:10.1136/bcr.04.2011.4057
  • Reminder of important clinical lesson

High-dose amoxicillin should be included in the empirical treatment of suspected meningitis in patients at risk of HIV infection

  1. Eliza Alexander2
  1. 1Renal Unit, Brighton and Sussex University Hospital, Brighton, UK
  2. 2Department of Microbiology, Brighton and Sussex University Hospital, Brighton, UK
  3. 3Department of HIV, Brighton and Sussex University Hospital, Brighton, UK
  1. Correspondence to Dr Ben Edward Michael Talbot, bentalbot{at}doctors.org.uk

Summary

The authors report on a case of Listeria rhomboencepahlitis in a previously undiagnosed HIV positive man. This case is of interest as the incidence of Listeria has increased dramatically in recent years and so may increase in the HIV-infected population. The organism is inherently resistant to cephalosporin antibiotics, empirically employed in the treatment of central nervous system infections and thus highlights the need to include amoxicillin in meningitis treatment regimes in patients at risk of HIV infection as well as the older and those known to be immuno-compromised.

Footnotes

  • Competing interests None.

  • Patient consent Obtained.

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