Plasmapheresis as rescue therapy for systemic lupus erthyematosus-associated diffuse alveolar haemorrhage
- 1Department of Renal, Guy’s and St Thomas’ Hospital Trust, London, UK
- 2Department of Nephrology and Transplantation, Guy’s and St Thomas’ Hospital Trust, London, UK
- Correspondence to Dr Simon Claridge,
Diffuse alveolar haemorrhage (DAH) is a rare complication of systemic lupus erythematosus (SLE), which can have a potentially lethal outcome. Conventional treatments of the condition include cyclophosphamide and intravenous immunoglobulins. Successful treatment with rituximab and plasmapheresis has also been described. The authors report the case of a woman recently diagnosed with SLE who developed DAH refractory to conventional treatment while on immunosuppressive treatment for class III lupus nephritis whose DAH responded to plasmapheresis.
Competing interests None.
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