BMJ Case Reports 2010; doi:10.1136/bcr.10.2010.3439
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Cryoglobulinaemia induced digital gangrene in a case of hepatitis C

  1. Simon W Dubrey1
  1. 1Department of Cardiology, Hillingdon Hospital, Uxbridge, UK
  2. 2Departmet of Haematology, Hillingdon Hospital, Uxbridge, UK
  1. Correspondence to Simon W Dubrey, simon.dubrey{at}


A 65-year-old woman presented with severe pain in the fingers of both hands (figure 1).

Figure 1

Hands of the patient with cryoglobulin-induced gangrene.

The patient was diagnosed with hepatitis C virus (HCV), following blood transfusion 30 years ago, and had developed the associated pathologies of cirrhosis and cryoglobulinaemia. Over the past 7 …

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