Practice of symptomatic treatment in the era of evidence-based medicine: report of 2 cases of diagnosis of Sheehan’s syndrome delayed till eighth decade
- Abdul Majid Wani1,
- Waleed Mohd Hussain1,
- Mousa Ali Al Mejally1,
- Abdulhakeem Amroon Banjar1,
- Khaled Shawkat Ali1,
- Amer Mohd Khoujah2,
- Sadeya Hanif Raja1,
- Mazen G Bafaraj2,
- Wail Al Miamini1,
- Mubeena Akhtar1
- 1Hera General Hospital, Makkah, 21955, Saudi Arabia
- 2Umm Al-Qura University, Makkah, 21955, Saudi Arabia
- Correspondence to Abdul Majid Wani,
- Published 6 May 2010
Sheehan’s syndrome, first described in 1937, is characterised by postpartum haemorrhage, pituitary necrosis, lactational failure and hypopitutarism. Presentation is variable and late presentations are not unusual due to partial ischaemic injury of the pituitary and gradual loss of endocrine function. A history of postpartum haemorrhage is usual but in some cases it is not elicited. Presentations such as malaise, fatigue, hypoglycaemia, decline in cognition, hyponatraemia, pancytopoenia, osteoporosis, secondary infertility, confusion and coma have all been reported. Two interesting cases of Sheehan’s syndrome are presented that were diagnosed in the eighth decade; one due to atypical presentation of recurrent hyponatraemia and confusion, another from hypoglycaemic coma and symptoms of malaise and lethargy.
Competing interests: None.
Patient consent: Patient/guardian consent was obtained for publication.