BMJ Case Reports 2010; doi:10.1136/bcr.08.2008.0821
  • Unusual presentation of more common disease/injury

Mitral valve involvement as a predominant feature of cardiac amyloidosis

  1. Philip Campbell2
  1. 1Institute of Cellular Medicine, Newcastle upon Tyne, UK
  2. 2Department of Cardiology, Royal Gwent Hospital, Newport, UK
  1. Correspondence to Girish Viswanathan, girishviswa{at}


Cardiac involvement in systemic amyloidosis carries poor prognosis with a median survival of 5 months.1 The authors report an unusual presentation of cardiac amyloidosis in the form of predominant mitral regurgitation. The patient responded very well to medical therapy with subsequent improvement of mitral valve dysfunction. The authors would like to highlight this multisystem involvement and the presence of a complex overlap of systemic features.


  • Competing interests None.

  • Patient consent Obtained.

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