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Rare disease
Transient osteoporosis associated with pregnancy: use of bisphosphonate in treating a lactating mother.
  1. N G Shenker1,
  2. M F Shaikh2,
  3. A S M Jawad3
  1. 1Department of Rheumatology, Cambridge University Hospitals NHS Foundation Trust, Addenbrooke's Hospital, Cambridge, UK
  2. 2Rheumatology Research Unit, Cambridge University Hospitals NHS Foundation Trust, Addenbrooke's Hospital, Cambridge, UK
  3. 3Department of Rheumatology, The Royal London Hospital, Whitechapel, London, UK
  1. Correspondence to M F Shaikh, malihashaikh{at}doctors.net.uk

Summary

Transient osteoporosis is a rare condition causing regional pain, immobility and functional compromise. The authors present the case of a pregnant lady with multiple sites of transient osteoporosis, including a stress fracture, successfully treated with intravenous pamidronate and a physical rehabilitation programme. The authors discuss the mechanisms for the syndrome and its overlap with complex regional pain syndrome type I; as well as the implications of bisphosphonate administration to a nursing mother. The authors also highlight the advantages of MRI over standard radiography when investigating unexplained foot pain.

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Footnotes

  • Competing interests None.

  • Patient consent Obtained.