Article Text
Unexpected outcome (positive or negative) including adverse drug reactions
Angioneurotic orolingual oedema following thrombolysis in acute ischaemic stroke
Summary
Alteplase used for thrombolysis in ischaemic stroke may be complicated by orolingual acute angioedema (OAA), a rare but potentially life-threatening side effect. We report the case of a 32-year-old woman who over 24 h experienced OAA after thrombolysis for an acute ischaemic left hemispheric stroke. We discuss the pathophysiology of this rare phenomenon.