BMJ Case Reports 2010; doi:10.1136/bcr.06.2010.3094
  • Unexpected outcome (positive or negative) including adverse drug reactions

Angioneurotic orolingual oedema following thrombolysis in acute ischaemic stroke

  1. C Lucas1
  1. 1Department of Neurology, Memory Center, Lille University Hospital, Lille, France
  2. 2Department of Intensive Care, Lille University Hospital, Lille, France
  1. Correspondence to C Lucas, clucas{at}


Alteplase used for thrombolysis in ischaemic stroke may be complicated by orolingual acute angioedema (OAA), a rare but potentially life-threatening side effect. We report the case of a 32-year-old woman who over 24 h experienced OAA after thrombolysis for an acute ischaemic left hemispheric stroke. We discuss the pathophysiology of this rare phenomenon.


  • Competing interests None.

  • Patient consent Obtained.

No Related Web Pages

Register for free content

The full text of all Editor's Choice articles and summaries of every article are free without registration

The full text of Images in ... articles are free to registered users

Only fellows can access the full text of case reports (apart from Editor's Choice) - become a fellow today, or encourage your institution to, so that together we can grow and develop this resource

Don't forget to sign up for content alerts so you keep up to date with all the case reports as they are published, and let us know what you think by commenting on the Editor's blog

Navigate This Article