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BMJ Case Reports 2010; doi:10.1136/bcr.06.2010.3094
  • Unexpected outcome (positive or negative) including adverse drug reactions

Angioneurotic orolingual oedema following thrombolysis in acute ischaemic stroke

  1. C Lucas1
  1. 1Department of Neurology, Memory Center, Lille University Hospital, Lille, France
  2. 2Department of Intensive Care, Lille University Hospital, Lille, France
  1. Correspondence to C Lucas, clucas{at}chru-lille.fr

Summary

Alteplase used for thrombolysis in ischaemic stroke may be complicated by orolingual acute angioedema (OAA), a rare but potentially life-threatening side effect. We report the case of a 32-year-old woman who over 24 h experienced OAA after thrombolysis for an acute ischaemic left hemispheric stroke. We discuss the pathophysiology of this rare phenomenon.

Footnotes

  • Competing interests None.

  • Patient consent Obtained.

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