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Rare disease
Primary amyloidosis presenting as cholestatic jaundice
  1. Lukasz T Polanski1,
  2. Sheraz R Markar2,
  3. Thomas Satyadas3,
  4. Raj Praseedom3,
  5. Ashley Shaw4
  1. 1Norfolk and Norwich University Hospital, Obstetrics and Gynaecology, Colney Lane, Norwich NR4 7UU, UK
  2. 2Addenbrooke’s Hospital, Cambridge Upper Gastrointestinal Surgery Unit, Cambridge University Hospitals NHS Foundation Trust, Hills Road, Cambridge CB2 0QQ, UK
  3. 3Addenbrooke’s Hospital, Cambridge Hepatobiliary Surgery Unit, Cambridge University Hospitals NHS Foundation Trust, Hills Road, Cambridge CB2 0QQ, UK
  4. 4Addenbrooke’s Hospital, Department of Radiology, Cambridge University Hospitals NHS Foundation Trust, Hills Road, Cambridge CB2 0QQ, UK
  1. Correspondence to Lukasz Polanski, lucas.polanski{at}hotmail.com

Summary

This case report describes a rare but fatal presentation of amyloidosis. Multiple organs and systems can be affected by the condition. Cholestatic jaundice is a infrequent manifestation of amyloidosis. An 80-year-old patient died within a month after onset of jaundice as a result of irreversible damage caused by deposition of amyloid. The relatively short period of time did not allow a tissue sample to be obtained from the patient and the final diagnosis was made postmortem.

https://doi.org/10.1136/bcr.06.2009.1974

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    Footnotes

    • Competing interests: None.

    • Patient consent: Patient/guardian consent was obtained for publication.