BMJ Case Reports 2010; doi:10.1136/bcr.04.2010.2925
  • Findings that shed new light on the possible pathogenesis of a disease or an adverse effect

The serotonin syndrome as a result of mephedrone toxicity

  1. Michael Sweeney2
  1. 1School of Medicine, NUI Galway, Galway, Ireland
  2. 2Emergency Department, Sligo General Hospital, Sligo, Ireland
  1. Correspondence to Gerard Garrett, g.garrett2{at}
  • Published 21 September 2010


A 22-year-old male presented to an emergency department by ambulance. His clinical picture included tachycardia, diaphoresis, hypertonia, hyper-reflexia and clonus. The patient became hyperthermic and deteriorated over the next hour. The principal substance ingested was mephedrone and appropriate treatment for the serotonin syndrome resulted in a sustained recovery over 15 h.


  • Competing interests None.

  • Patient consent Obtained.

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