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The ubiquitous Scedosporium apiospermum is a saprophytic filamentous fungus that causes a wide range of human infections that affect virtually every organ in the body. S apiospermum has been described as one of the major fungal agents of chronic colonisation of airways in patients with cystic fibrosis (CF).1 This organism is the second most frequent filamentous fungus that can be found in patients with CF after Aspergillus fumigatus. The prevalence of S apiospermum from bronchial secretions of patients with CF is reported to be 0.7–9%.1–3 Although this fungus is usually considered a simple endobronchial colonising agent in CF without pathological effects for the host, there have been some reported cases of invasive infections due to S apiospermum in patients with CF, including one case after lung transplantation.1 4 However, the pathogenicity of this organism in CF is still not well established.
Acknowledgments
This article has been adapted from Nagano Yuriko, Cherie Millar B, Goldsmith Colin E, Stuart Elborn J, Rendall Jackie, Moore John E. Emergence of Scedosporium apiospermum in patients with cystic fibrosis Archives of Disease in Childhood 2007;92:607
Footnotes
Competing interests: None.