Pseudomembranous colitis in four patients with cystic fibrosis following lung transplantation
- Institute of Cellular Medicine, University of Newcastle and The Freeman Hospital, High Heaton, Newcastle upon Tyne, NE7 7DN, UK
- Paul A Corris, paul.Corris{at}ncl.ac.uk
- Published 8 May 2009
Summary
In the present study, 4 patients with cystic fibrosis undergoing lung transplantation (from a total of 137) who developed fulminant pseudomembranous colitis are described. Initial presentation was variable and the mortality rate was 50% despite urgent colectomy. In one case the presenting abdominal distension was thought to be due to meconium ileus equivalent. It is concluded that Clostridium difficile colitis may be a difficult diagnosis in patients with cystic fibrosis and follows a fulminant course after lung transplantation.
Footnotes
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Competing interests: none.








