Collision of advanced gastric adenocarcinoma and gastrointestinal stromal tumour: a case report
- Akihiro Toyoda1,
- Akira Komaba2,
- Hiroaki Yoshizumi2,
- Ryosuke Hanaoka2,
- Syoko Sakuma2,
- Akira Ichinohe2,
- Hidetada Kawana1,
- Kenichi Harigaya1
- 1Chiba University Graduate School of Medicine, Molecular and Tumor Pathology, 1-8-1 Inohana, Chuo-ku, Chiba, 260-8670, Japan
- 2JA Kouseiren Kamitsuga General Hospital, 1-1033 Shimoda, Kanuma, 322-8550, Japan
- Akihiro Toyoda, atoyoda{at}faculty.chiba-u.jp
- Published 22 November 2009
Summary
We present a case of an 83-year-old female patient with a collision tumour of an advanced Borrmann type 4 gastric cancer and a large gastric gastrointestinal stromal tumour (GIST). According to the deformity of the gastric wall caused by the GIST, type 4 cancer was difficult to identify by oesophagogastroduodenoscopy (OGD). The patient died of progressive gastric cancer related disease. While the mechanism of histogenesis of the simultaneous adenocarcinoma and GIST remains to be determined, the present case suggests that gastric adenocarcinoma has a more adverse effect on prognosis than does GIST. Additionally, this case suggests that thorough inspection of GIST patients is required at the OGD and at the pathology facility, in order to avoid overlooking the underlying cancer.
Footnotes
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Competing interests: none.
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Patient consent: Patient/guardian consent was obtained for publication
