BMJ Case Reports 2009; doi:10.1136/bcr.07.2008.0475
  • Reminder of important clinical lesson

Persistent high nevirapine blood level with DRESS syndrome 12 days after interruption of antiretroviral therapy

  1. Alice Breining1,
  2. Amelie Guihot1,
  3. Dominique Warot1,
  4. Ana Canestri1,
  5. Gilles Peytavin2,
  6. Francois Bricaire1,
  7. Eric Caumes1
  1. 1
    Pitie Salpetriere Hospital, Infectious Disease, 47–83 Boulevard de l Hôpital, Paris, 75013, France
  2. 2
    Claude Bernard Bichat Hospital, Toxicology, 46 Rue Henri Huchard, Paris, 75018, France
  1. Alice Breining, alicebreining{at}
  • Published 17 March 2009


Nevirapine is an antiretroviral agent associated with drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome. Such a case in an immunocompetent woman recently treated with nevirapine for postexposure HIV prophylaxis is reported here. Despite a period of 12 days after interruption of treatment, a high blood level of nevirapine was still observed.


  • Competing interests: None.

  • Patient consent: Patient/guardian consent was obtained for publication.

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