BMJ Case Reports 2009; doi:10.1136/bcr.06.2008.0334
  • Unexpected outcome (positive or negative) including adverse drug reactions

Oxaliplatin-induced coronary artery spasm: first report of an important side-effect

  1. Jens Samol1,
  2. Ashita Waterston2
  1. 1
    Beatson Oncology Centre, Medical Oncology, Gartnavel General Hospital, 1053 Great Western Road, Glasgow G12 0YN, UK
  2. 2
    Beatson Oncology Centre, Medical Oncology, West of Scotland Cancer Centre, 1053 Great Western Road, Glasgow G12 0YN, UK
  1. jens.samol{at}
  • Published 26 February 2009


A 67-year-old woman with metastatic colorectal cancer was given her first oxaliplatin infusion as part of the XELOX protocol. She developed chest pain with ECG changes leading subsequently to a diagnosis of coronary artery spasm. To our knowledge, this is the first report of oxaliplatin-induced coronary artery spasm.


  • Competing interests: none.

  • Patient consent: Patient/guardian consent was obtained for publication.

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