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BMJ Case Reports 2009; doi:10.1136/bcr.02.2009.1542
  • Findings that shed new light on the possible pathogenesis of a disease or an adverse effect

Sudden death caused by Staphylococcus aureus carrying Panton–Valentine leukocidin gene in a young girl

  1. Thanh-Van Trieu1,
  2. Joel Gaudelus1,
  3. Sophie Lefevre1,
  4. Anne Marie Teychene1,
  5. Isabelle Poilane2,
  6. Anne Colignon2,
  7. Jerome Etienne3,
  8. Loïc de Pontual1
  1. 1
    Service de Pédiatrie, Hôpital Jean Verdier, Avenue du 14 Juillet, Bondy, 93140, France
  2. 2
    Service de Microbiologie, Hôpital Jean Verdier, Avenue Du 14 Juillet, Bondy, 93140, France
  3. 3
    INSERM U851, Université de Lyon 1, Centre National de Référence des Staphylocoques, 59 boulevard Pinel, Lyon, 69677, France
  1. Loïc de Pontual, loic.de-pontual{at}jvr.aphp.fr
  • Published 4 November 2009

Summary

Staphylococcus aureus carrying the Panton–Valentine leukocidin (PVL) gene could be the source of both recurrent furunculosis or abscesses and severe infections, mainly necrotising pneumonia. We present the case of a young girl from consanguineous parents who died suddenly. The postmortem examination revealed necrotising pneumonia due to a PVL producing Staphylococcus aureus strain, raising the question of the role of the host’s immune status in this infection.

Footnotes

  • Competing interests: none.

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