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Findings that shed new light on the possible pathogenesis of a disease or an adverse effect
Primary spleen lymphoma associated with hepatitis C virus infection
  1. Ricardo Cotta-Pereira1,
  2. Roberta Acar2,
  3. Carlos Eduardo Brandão Mello3,
  4. Antonio Carlos Iglesias1,
  5. Carlos Alberto Basílio-de-Oliveira2
  1. 1Department of Surgery, Gaffrée & Guinle University Hospital, Rio de Janeiro, Brazil
  2. 2Department of Pathology, Gaffrée & Guinle University Hospital, Rio de Janeiro, Brazil
  3. 3Department of Internal Medicine, Gaffrée & Guinle University Hospital, Rio de Janeiro, Brazil
  1. Correspondence to Ricardo Cotta-Pereira, rc{at}rtcp.com.br

Summary

Lymphoproliferative disorders associated with hepatitis C virus (HCV) make up a heterogeneous group of diseases, including lymphomas. It was only recently that HCV was recognised as being a potential cause for the development of non-Hodgkin's lymphoma. The authors report a case of an older woman with chronic hepatitis C who developed primary spleen lymphoma. This case report points out the pathophysiological mechanisms of this disease and the importance of considering this disease in the differential diagnosis of patients with chronic HCV infection.

https://doi.org/10.1136/bcr.11.2010.3474

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    Footnotes

    • Competing interests None.

    • Patient consent Obtained.