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CASE REPORT
Synchronous endometrioid carcinoma of the endometrium and small cell neuroendocrine carcinoma of the cervix: a rare combination
  1. Tripti Nakra1,
  2. Rituparna Biswas2,
  3. Rambha Pandey3,
  4. Rajni Yadav4
  1. 1Pathology, All India Institute of Medical Sciences, New Delhi, India
  2. 2Radiotherapy, All India Institute of Medical Sciences, New Delhi, India
  3. 3Radiation Oncology, All India Institute of Medical Sciences, New Delhi, India
  4. 4Department of Pathology, All India Institute of Medical Sciences, New Delhi, India
  1. Correspondence to Dr Rajni Yadav, drrajniyadav{at}gmail.com

Summary

Synchronous multiple primaries of female genital tract are uncommon, with the most frequently encountered combination being of endometrium and ovary. Concurrent primary tumours of endometrium and cervix are rare. We report a case of coexistent endometrioid carcinoma of the endometrium and small cell neuroendocrine carcinoma of the cervix in 48-year-old woman who presented with menometrorrhagia and was detected to have metastases to distant sites on imaging. She underwent multimodality treatment which resulted in a significant reduction in the tumour bulk.

  • chemotherapy
  • gynecological cancer
  • pathology

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Footnotes

  • Contributors TN did acquisition of data, interpretation and drafting of the article. RB did acquisition and interpretation of the data along with writing part of manuscript. RP participated in the designing and interpretation of the data along with reviewing the discussion part of the manuscript. RY participated in conception and design, did critical revision for intellectual content and drafting of the article. All the authors approved to the final version of the article and agreed to be accountable for the accuracy and integrity of the article.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Patient consent Obtained.

  • Provenance and peer review Not commissioned; externally peer reviewed.