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Unexpected outcome (positive or negative) including adverse drug reactions
Acute myocardial infarction following ingestion of a non-selective non-steroidal anti-inflammatory drug
  1. Masliza Mahmod,
  2. Ika Faizura Mohd Nor,
  3. Oteh Maskon
  1. National University of Malaysia, Department of Medicine, Jalan Yaacob Latiff, Bandar Tun Razak, Cheras, Kuala Lumpur, 56000, Malaysia
  1. Correspondence to Masliza Mahmod, mmd{at}mail.hukm.ukm.my

Summary

While selective non-steroidal anti-inflammatory drugs, namely cyclo-oxygenase-2 (COX 2) inhibitors, are known to be associated with acute myocardial infarction, little is known about the cardiovascular safety of the non-selective non-steroidal anti-inflammatory drugs. We report the case of a 44-year-old man who developed anaphylactic reaction and acute inferior myocardial infarction following ingestion of a non-selective anti-inflammatory drug, diclofenac sodium. Coronary angiography revealed a large thrombus in the right coronary artery which was partially removed by intracoronary catheter aspiration. Complete resolution of the remaining thrombus was achieved after treatment with an oral anticoagulant.

https://doi.org/10.1136/bcr.02.2009.1549

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    Footnotes

    • Competing interests: None.

    • Patient consent: Patient/guardian consent was obtained for publication.