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Published 20 September 2009
Cite this as: BMJ Case Reports 2009 [doi:10.1136/bcr.11.2008.1288]
Copyright © 2009 by the BMJ Publishing Group Ltd.

Rare disease

Culture-negative endocarditis: "whatever remains, however improbable, must be the truth"; the importance of asking the right questions!

Amar Bhavin Kachhia, Douglas Wan, Andrew Whittaker, Naeem Shaukat, Salman S Nishtar, James Cullen

Cardiology, Kettering General Hospital NHS Trust, Rothwell Road, Kettering, Northamptonshire, NN16 8UZ, UK

Correspondence to:
Amar Bhavin Kachhia, thisisitamar{at}gmail.com

SUMMARY

The complicated case of a patient with recurrent culture-negative endocarditis with a history of repeated mitral valve replacement is described. Investigations disqualified common pathology but serology revealed a diagnosis of Q fever endocarditis. The ongoing problematic management of this patient is described, followed by a brief review of the clinical features, investigations and treatment of Q fever.


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