Rare disease
Episodic paralysis in a young male
1 University of Wales College of Medicine, Department of Endocrine and Diabetes Sciences, Room 260, University Hospital of Wales, Heath Park, Cardiff CF14 4XW, UK
2 Newholme, Maplewood Avenue, Cardiff CF14 2LZ, UK
3 University of Wales College of Medicine, Heath Park, Cardiff CF14 4XW, UK
Correspondence to:
Anna Claire de Lloyd, annade_lloyd{at}hotmail.com
A 19-year-old Caucasian male presented acutely describing several episodes of profound paralysis. At the time of admission he had recovered completely and his neurological examination and routine biochemistry were normal. A diagnosis of thyrotoxic periodic paralysis was made after the thyroid function tests returned confirming hyperthyroidism. He was given β blockers and received a block and replacement regime before proceeding on to radioactive iodine therapy. He suffered a relapse of hyperthyroidism and paralysis following the radioiodine and required carbimazole for a short time before becoming permanently hypothyroid. Euthyroidism is now maintained with thyroxine replacement therapy and he has had no further episodes of paralysis.
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