Rare disease
A metabolic muscle disease
1 Royal Hallamshire Hospital, Neurology, Glossop Road, Sheffield, South Yorkshire S10 2RA, UK
2 Royal Hallamshire Hospital, Histopathology, Glossop Road, Sheffield, South Yorkshire S10 2RA, UK
Correspondence to:
Muhammad Khizar Rafiq, drmkrafiq{at}hotmail.com
A 61-year-old woman presented with a life long history of fatigability which worsened on exertion. She became fearful of exercising and thus was labelled as "lazy" by family and friends. After being started on simvastatin she was found to have raised creatine kinase (CK) values, which remained elevated despite stopping the drug. On the basis of the history, McArdle disease was suspected and a muscle biopsy confirmed it.
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