Findings that shed new light on the possible pathogenesis of a disease or an adverse effect
Sudden death caused by Staphylococcus aureus carrying Panton–Valentine leukocidin gene in a young girl
1 Service de Pédiatrie, Hôpital Jean Verdier, Avenue du 14 Juillet, Bondy, 93140, France
2 Service de Microbiologie, Hôpital Jean Verdier, Avenue Du 14 Juillet, Bondy, 93140, France
3 INSERM U851, Université de Lyon 1, Centre National de Référence des Staphylocoques, 59 boulevard Pinel, Lyon, 69677, France
Correspondence to:
Loïc de Pontual, loic.de-pontual{at}jvr.aphp.fr
Staphylococcus aureus carrying the Panton–Valentine leukocidin (PVL) gene could be the source of both recurrent furunculosis or abscesses and severe infections, mainly necrotising pneumonia. We present the case of a young girl from consanguineous parents who died suddenly. The postmortem examination revealed necrotising pneumonia due to a PVL producing Staphylococcus aureus strain, raising the question of the role of the hosts immune status in this infection.
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