Novel treatment (new drug/intervention; established drug/procedure in new situation)
Treatment of Buerger disease (thromboangiitis obliterans) with bosentan: a case report
Hospital Universitario Getafe, Angiology and Vascular Surgery, Carretera de Toledo Km 12500, Getafe, 28905, Spain
Correspondence to:
Joaquin De Haro, deharojoaquin{at}yahoo.es
Buerger disease (thromboangiitis obliterans) is a non-atherosclerotic segmental inflammatory disease strongly associated with tobacco use, and it affects small and medium-sized blood vessels in the upper and lower extremities. The only known treatment for this disease is complete discontinuation of tobacco use. This report describes the case history of a woman with Buerger disease treated with the oral dual endothelin receptor antagonist bosentan. It is believed that this is the first description in the literature of this use for bosentan.
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