Unexpected outcome (positive or negative) including adverse drug reactions
Diffuse alveolar haemorrhage secondary to warfarin therapy for atrial fibrillation: a case report and literature review
1 King Abdulaziz Medical City for National Guards, Internal Medicine - Code 1443, PO Box 22490, Riyadh 11426, Saudi Arabia
2 King Abdulaziz Medical City, ICU, PO Box 22490, Riyadh 11426, Saudi Arabia
3 King Abdulaziz Medical City, Medicine, PO Box 22490, Riyadh 11426, Saudi Arabia
Correspondence to:
Abdelkarim Waness, n4a1w{at}yahoo.com
Alveolar haemorrhage is a rare and serious medical emergency with many causes. Diffuse alveolar haemorrhage due to warfarin therapy has been rarely reported in the literature. In this paper, we describe the case of 62-year-old woman with a history of chronic atrial fibrillation treated with warfarin, who was admitted to our institution with haemoptysis and dyspnoea. Alveolar haemorrhage was suspected clinically and subsequently confirmed by bronchoscopy. The patient required aggressive treatment with fresh frozen plasma, vitamin K and mechanical ventilation with a successful outcome. We emphasise the need for early diagnosis and fast therapeutic intervention, especially with over-anticoagulation (INR >9), in patients with this rare and potentially lethal condition.
CiteULike 
Complore 
Connotea 
Del.icio.us 
Digg 
Reddit 
Technorati What's this?
- Full Text
- Submit a response
- Alert me when this article is cited
- Alert me when eLetters are posted
- Alert me if a correction is posted
Services
- Email this link to a friend
- Similar articles in this journal
- Add article to my folders
- Download to citation manager
- Request Permissions
Citing Articles
Google Scholar
PubMed
Topic Collections
-
Arrhythmias
-
Drugs: cardiovascular system
-
Unwanted effects / adverse reactions
-
Radiology
-
Respiratory medicine
Bookmark with
Register for free content
The full text of all Editor's Choice articles and summaries of every article are free without registration
The full text of Images in ... articles are free to registered users
Only fellows can access the full text of case reports (apart from Editor's Choice) - become a fellow today, or encourage your institution to, so that together we can grow and develop this resource
Don't forget to sign up for content alerts so you keep up to date with all the case reports as they are published, and let us know what you think by commenting on the Editor's blog
