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Published 17 March 2009
Cite this as: BMJ Case Reports 2009 [doi:10.1136/bcr.07.2008.0480]
Copyright © 2009 by the BMJ Publishing Group Ltd.

Novel treatment (new drug/intervention; established drug/procedure in new situation)

Psychopharmacological treatment of behavioural problems in Sanfilippo syndrome

Paramala Santosh1, Jennifer Ruth Parker2, Lynn Jones3

1 Centre for Interventional Paediatric Psychopharmacology, Child and Adolescent Mental Health, Great Ormond Street Hospital, Great Ormond Street, London, WC1N 3JH, UK
2 Child and Adolescent Mental Health, Great Ormond Street Hospital, Great Ormond Street, London, WC1N 3JH, UK
3 Child and Adolescent Psychiatry, Cambridgeshire Mental Health Trust, Elizabeth House, Cambridge, CB21 5EF, UK

Correspondence to:
Paramala Santosh, santop{at}gosh.nhs.uk

SUMMARY

The present report illustrates successful use of psychotropic medication targeted at symptom clusters of behavioural disturbance in a 7-year-old girl with Sanfilippo syndrome, a mucopolysaccharidosis. By identifying and targeting symptom clusters, psychotropic medication was prescribed with significant results. This approach to treatment of behavioural disturbance in Sanfilippo syndrome has not been previously described to our knowledge. Caution with regards side effects and interaction of medication is advised.


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