Reminder of important clinical lesson
A case for varicella vaccination in the immunosuppressed
Royal Free Hospital NHS Trust, Pond Street, London NW3 2XA, UK
Correspondence to:
Michael Vaclav Holmes, mvholmes{at}googlemail.com
A middle-aged man with long-standing Crohn disease maintained in remission on low-dose immunosuppression presented with abdominal pain. Over the following few days he developed a vesicular rash, became dyspnoeic, confused and had two seizures. Despite high-dose intravenous aciclovir, he died. Disseminated varicella zoster virus, the cause of his death, could potentially have been prevented had he received varicella vaccination at an earlier stage.
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