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Published 6 March 2009
Cite this as: BMJ Case Reports 2009 [doi:10.1136/bcr.09.2008.0857]
Copyright © 2009 by the BMJ Publishing Group Ltd.

Novel treatment (new drug/intervention; established drug/procedure in new situation)

Good outcome after rituximab treatment for a mixed warm and cold autoimmune haemolytic anaemia

Brigitte Granel1, Pascal Rossi1, Fanny Bernard1, Isabelle Dettori2, Regis Costello3, Anne Laurence Demoux1, Denis Bagneres1, Pierre Lafforgue4, Yves Frances1

1 Hopital Nord, Internal Medicine, Chemin des Bourrely, Marseille, 13915, France
2 Etablissement Français du Sang, Boulevard Baille, Marseille, 13385, France
3 Hopital Nord, Haematology, Chemin des Bourrely, Marseille, 13915, France
4 Hopital Conception, Rheumatology, Boulevard Baille, Marseille, 13385, France

Correspondence to:
Brigitte Granel, bgranel{at}ap-hm.fr

SUMMARY

Mixed warm and cold autoimmune anaemia is a rare haemolytic anaemia that is commonly associated with lymphoproliferative disorders and autoimmune diseases. Although steroid therapy is the first-line treatment, rituximab represents a good alternative. The present study reports on a successful treatment with rituximab in a young woman suffering from a mixed warm and cold autoimmune haemolytic anaemia associated with a mixed connective tissue disease.


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