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Published 26 June 2009
Cite this as: BMJ Case Reports 2009 [doi:10.1136/bcr.01.2009.1501]
Copyright © 2009 by the BMJ Publishing Group Ltd.

Rare disease

A case of Hashimoto encephalopathy in a Malay woman with Graves disease

Chai Soon Ngiu, Norlinah M Ibrahim, Wan Nur Nafisah Wan Yahya, Hui Jan Tan, Norlaila Mustafa, Hamidon Basri, Raymond Azman Ali

Hospital UKM, Department of Medicine, Jalan Yaacob Latiff, Kuala Lumpur, 56000, Malaysia

Correspondence to:
Norlinah M Ibrahim, norlinah{at}gmail.com

SUMMARY

Hashimoto encephalopathy (HE) is a poorly recognised steroid-responsive encephalopathy, with prominent neuropsychiatric features. Diagnosis is often difficult due to its heterogeneous clinical presentation, especially since the thyroid status or anti-thyroid antibody titres may not be related to the disease state. Here, the case of a 23-year-old Malay woman with Graves disease who presented with progressive encephalopathy diagnosed as HE is presented. She responded dramatically to high dose intravenous and then oral corticosteroid. A month after the initiation of treatment, she regained full independency.


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