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Published 21 June 2009
Cite this as: BMJ Case Reports 2009 [doi:10.1136/bcr.02.2009.1538]
Copyright © 2009 by the BMJ Publishing Group Ltd.

Unusual association of diseases/symptoms

Transient hypopituitarism in a patient with nephropathia epidemica

Christina Jost1, Robert Krause2, Winfried Graninger1, Kurt Weber1

1 Medical University Hospital Graz, Rheumatology, Auenbruggerplatz 15, Graz, 8036, Austria
2 Medical University Hospital Graz, Pulmology, Auenbruggerplatz 20, Graz, 8036, Austria

Correspondence to:
Christina Jost, christina.jost{at}klinikum-graz.at

SUMMARY

Involvement of the pituitary gland is only rarely observed in hantavirus infection. This report describes the case of a patient who had transient hypopituitarism requiring hormonal replacement therapy due to hypophysitis as a result of Puumala virus infection. MRI studies revealed oedematous swelling of the gland as a morphological correlate. This report provides new evidence that hypopituitarism can be a serious complication in Puumala virus infection and highlights the clinical implications of this disorder.


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