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Published 1 June 2009
Cite this as: BMJ Case Reports 2009 [doi:10.1136/bcr.09.2008.0894]
Copyright © 2009 by the BMJ Publishing Group Ltd.

Learning from errors

Benign endoscopic biopsies may be a red herring

Laith Alrubaiy1, Waqar Ahmed2, Jonathan Sutton1

1 Ysbyty Gwynedd, Bangor, Bangor LL57 2PW, UK
2 Ysbyty Gywnedd, Medicine, Bangor, Bangor LL57 2PW, UK

Correspondence to:
Laith Alrubaiy, laithalrubaiy{at}gmail.com

SUMMARY

A 64-year-old man presented with haematemesis and melena. Repeated endoscopies showed extensive candidiasis with an exophytic mass like a shelf of tumour. Biopsies showed chronic inflammatory changes with candidiasis without evidence of malignancy. His only complaint was feeling tired and loss of energy. There was no dysphagia but slight retrostenal discomfort on swallowing. Computed tomography scan reported an opacification in the right upper lobe adjacent to the mediastinum. This contained air bronchograms and several irregular air filled cavities. There was significant mediastinal adenopathy. Two endoscopies were done after that and both of them demonstrated a fistulous connection with the bronchial tree. Biopsies failed to show any neoplasm. The patient underwent a three stage oesophagectomy with removal of the adjacent lung lobe and a reconstructive procedure. The resected mass was sent for histopathology which showed a well differentiated squamous cell carcinoma of the oesophagus which locally invaded the lung.


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