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Published 26 July 2009
Cite this as: BMJ Case Reports 2009 [doi:10.1136/bcr.03.2009.1671]
Copyright © 2009 by the BMJ Publishing Group Ltd.

Unusual presentation of more common disease/injury

Sudden onset proptosis secondary to cavernous sinus thrombosis from underlying mandibular dental infection

Robin Gwynne Jones1, Brendan Arnold2

1 Otago District Health Board, Ophthalmology, Eye Department, Second Floor, 201 Great King Street, Private Bag 1921, Dunedin, Otago, 9054, New Zealand
2 Otago District Health Board, Intensive Care, 5A, 201 Great King Street, Private Bag 1921, Dunedin, Otago, 9054, New Zealand

Correspondence to:
Robin Gwynne Jones, robingjones{at}gmail.com

SUMMARY

The present report concerns a patient who presented with a 4-day history of left-sided facial pain arising from a pre-existing dental infection and progressive shortness of breath. The patient had a previous diagnosis of rheumatoid arthritis and was being treated with methotrexate. The rapid development of a right eye proptosis necessitated urgent decompression with a lateral canthotomy and cantholysis. Imaging revealed a left facial abscess, cavernous sinus thrombosis (CST), bilateral internal jugular thrombosis and multiple lung abscesses. Blood cultures yielded Streptococcus constellatus, a member of the Peptostreptococcus family. The patient was admitted to the intensive care unit (ICU) with respiratory failure and septic shock. She was treated with intravenous meropenem and clindamycin, and anticoagulated. Despite early intervention, the patient developed a middle cerebral artery infarct. Over a 3-week period she was gradually weaned from vasopressor and ventilatory support.


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