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Published 2 February 2009
Cite this as: BMJ Case Reports 2009 [doi:10.1136/bcr.09.2008.0927]
Copyright © 2009 by the BMJ Publishing Group Ltd.

Novel treatment (new drug/intervention; established drug/procedure in new situation)

Successful repeated treatment with high dose cyclophosphamide and autologous blood stem cell transplantation in CIDP

Hans W Axelson1, Gunnar Öberg2, Håkan Askmark3

1 Clinical Neurophysiology, Uppsala University Hospital, Uppsala, SE-751 85, Sweden
2 Haematology, Uppsala University Hospital, Uppsala, SE-751 85, Sweden
3 Neurology, Uppsala University Hospital, Uppsala, SE-751 85, Sweden

Correspondence to:
hans.axelson{at}akademiska.se

SUMMARY

Chronic inflammatory demyelinating polyneuropathy (CIDP) is characterised by the occurrence of symmetrical weakness and sensory impairment in arms and legs. The course is relapsing or chronic and progressing. CIDP is considered to be an autoimmune disease, which is supported by the beneficial response to immunomodulating therapies in most patients. We report on a patient with CIDP who has been in remission for more than 3 years after treatment with high dose cyclophosphamide and autologous blood stem cell transplantation in CIDP on two occasions.


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