Rare disease
The "fish-vertebra" sign
1 Guy’s and St Thomas’, NHS Trust, London, SE1, UK
2 ‘Evangelismos’ General Hospital, Athens, Athens, 11521, Greece
Correspondence to:
ntagiopoulos{at}hotmail.com
The "fish-vertebra" sign appears as biconcave lumbar vertebrae with bone softening in lateral and posterior–anterior radiographs of the spine as an exaggeration of the normal concavity of the superior and inferior surfaces of one or more vertebral bodies. This is due to ischaemia of the central growth plate of the spine, and is typically seen in sickle cell disease.
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