Findings that shed new light on the possible pathogenesis of a disease or an adverse effect
Corticobasal syndrome due to a thalamic tuberculoma and focal cortical atrophy
1 Department of Neurology, Nizam’s Institute of Medical Sciences, Punjagutta, Hyderabad, India
2 Department of Radiology, Krishna Institute of Medical Sciences, Minister Road, Hyderabad, India
3 Department of Neurology, Kamineni Hospitals, LB nagar, Hyderabad, India
4 Department of Radiology, Nizam’s Institute of Medical Sciences, Punjagutta, Hyderabad, India
Correspondence to:
alladisuvarna{at}hotmail.com
Corticobasal syndrome (CBS) is characterised by asymmetric apraxia, cortical sensory loss, extrapyramidal features and cognitive decline. Although CBS is classically described as a taupathy, heterogeneity of its aetiology is increasingly recognised. Clinical presentation of CBS appears to reflect areas of the brain involved and not necessarily the nature of the underlying pathology. We report a patient in whom resolution of a thalamic tuberculoma was associated with progressive atrophy of the parietotemporal cortex, resulting in an unusual presentation of CBS
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