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Published 2 February 2009
Cite this as: BMJ Case Reports 2009 [doi:10.1136/bcr.08.2008.0687]
Copyright © 2009 by the BMJ Publishing Group Ltd.

Findings that shed new light on the possible pathogenesis of a disease or an adverse effect

Loss of exploratory vertical saccades after unilateral frontal eye field damage

Tobias Pflugshaupt, Thomas Nyffeler, Roman von Wartburg, Christian W Hess, René M Müri

Perception and Eye Movement Laboratory, Departments of Neurology and Clinical Research, University Hospital Bern, Bern, 3010, Switzerland

Correspondence to:
rene.mueri{at}insel.ch

SUMMARY

Despite their relevance for locomotion and social interaction in everyday situations, little is known about the cortical control of vertical saccades in humans. Results from microstimulation studies indicate that both frontal eye fields (FEFs) contribute to these eye movements. Here, we present a patient with a damaged right FEF, who hardly made vertical saccades during visual exploration. This finding suggests that, for the cortical control of exploratory vertical saccades, integrity of both FEFs is indeed important.


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